AMERICAN SENTINEL N521 ADVANCED PHARMACOLOGY

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Course Description

Focuses on the theoretical background and the principles of pharmacokinetics, pharmacodynamics, and pharmacotherapeutics of prescribed and over-the- counter drugs, and natural products commonly used in the advanced practice nurse’s management of acute and chronic illnesses, and in the general wellbeing of persons throughout the lifespan. Students learn to employ therapeutic decision-making in drug selection and evaluation in the course of patient care within the context of knowledge concerning pathophysiology and current pharmacological research. Additionally, students monitor and assess the effectiveness of drug therapy and formulate clinical care and teaching plans for persons from diverse populations regarding safe and effective use of drugs and natural products. Reviews patient education, legal, ethical and economic issues. AMERICAN SENTINEL N521 ADVANCED PHARMACOLOGY

Credits: 3 semester credits
Prerequisites: none

Learning Outcomes

Upon completion of this course, students will be able to:

Examine advanced pharmacokinetic and pharmacodynamics concepts as they relate to pathophysiologic changes in patients across the lifespan.
Identify the fundamental principles of pharmacology related to prescribed drugs, over-the-counter drugs and natural products.
Discuss the mechanism of action of each major drug class and natural product at the molecular/cellular and organ/organ system level.
Evaluate common side effects and interactions associated with the major classes of drugs.
Utilize evidence-based advanced nursing and pharmacological interventions in select case studies to resolve complex and biological, psychological, physiological and pathophysiologic conditions.
Synthesize research and evidence of pharmacological concepts that guides clinical judgment to develop a therapeutic regimen that maximizes efficacy and maintains quality while minimizing adverse effects.
Differentiate between therapeutic and adverse effects of pharmacological interventions and inappropriate use patterns, such as polypharmacy and polysubstance abuse interactions.
Teach patients, family members, and others from diverse populations regarding safe and effective use of drugs and natural products.
Determine nursing prescriptive privileges, parameters and scope of practice, and restrictions as delineated in federal and state laws and regulations, including state nurse practice acts.

Program Outcomes

Graduates of the MSN program will be able to:

Integrate roles as leaders and collaborators in various healthcare settings.
Use theoretical knowledge to guide graduate nursing practice.
Analyze models that expand the role of nurses in a global society.
Evaluate legislation, policies, and economics as applied to the current healthcare environment.
Appraise research to enhance professional nursing practice.

University Principles and MSN Program Learning Outcomes Aligned with this Course

Accountability:
Analyze models that expand the role of nurses in a global society.
Use theoretical knowledge to guide advanced nursing practice.

Citizenship:
Evaluate legislation, policies, and economics as applied to the current healthcare environment.

Leadership:
Integrate roles as leaders and collaborators in various healthcare settings.

Scholarship:
Appraise research to enhance professional nursing practice.

Quality and Safety in Nursing Education (QSEN) Competencies

Aligned competencies are included here in a list. For more information view www.qsen.org and select Competencies to review detailed information on the items listed below:

AMERICAN SENTINEL N521 ADVANCED PHARMACOLOGY COURSE MATERIALS, TECHNOLOGY AND SKILLS

Required Textbooks

Arcangelo, V. P., & Peterson, A. M. (2017). Pharmacotherapeutics for advanced practice: A practical approach (4^th ed.). Philadelphia, PA: Wolters Kluwer/Lippincott Williams & Wilkins.
ISBN-13: 9781496319968

American Psychological Association. (2010). Publication manual of the American Psychological Association (6th ed.). Washington, DC: Author.
ISBN-13: 978-1433805615
ISBN-10: 1433805618

Learning Materials

American Sentinel University Library Nursing Reference Center-Drug Information—Includes Davis’s Drug Guide for Nurses and AHFS Drug Information Essentials.
U.S. Food & Drug Administration: Provides “safety information about prescription drugs to help consumers and healthcare professionals make well-informed decisions about medication use.”
RxMED: “…Contains documented, authoritative and detailed information on over 3000 prescription pharmaceuticals. While this information is mainly presented for doctors, patients will find it valuable as well. These listings cover general pharmacology, indications, warnings, dosage and adverse effects information for each pharmaceutical monograph.”
RxList: “RxList is an online medical resource dedicated to offering detailed and current pharmaceutical information on brand and generic drugs. Founded by pharmacists in 1995, RxList is the premier Internet Drug Index resource. Our knowledgeable staff at RxList continuously reviews and updates the site with articles written by pharmacists and physicians and data provided by credible and reliable sources like the FDA and First Data Bank, Inc. to ensure the most accurate and beneficial information is provided.”
SafeMedication.com: “SafeMedication.com features easy-to-read information on more than 12,000 drug products that are approved by the Food & Drug Administration (FDA). It provides user-friendly information about both prescription and over-the-counter (OTC, non-prescription) medications in about 1000 monographs. This information is based on the American Society of Health-System Pharmacists’ drug information resources that are developed independently by pharmacists and other medication experts. Their mission is to provide a foundation for safe and effective drug therapy based on scientific evidence. The information is prepared according to guidelines established for useful written consumer information by the FDA and an expert committee established by the U.S. Department of Health and Human Services. This means that the information you find here is free from the influence of manufacturers, insurers, and other special interests.” AMERICAN SENTINEL N521 ADVANCED PHARMACOLOGY
Allied Vaccine Group: “…Is comprised of websites dedicated to presenting valid scientific information about the sometimes confusing subject of vaccines. Think of this page as your portal to the real world of vaccines, a world based on scientific research, followed by honest disclosure of the research results — pro and con.
CenterWatch Clinical Trials Listing Service: “Our mission is to be the leading source of clinical trials information for both clinical research professionals and patients. To support our mission, we offer several professional, educational and informative services and resources from news and analysis on the industry to trial listings seeking study volunteers. CenterWatch offers several services and resources specifically to patients. With our Clinical Trial Listing Service we are able to provide patients unbiased information on clinical trials, with a clinical trial database that contains thousands of currently enrolling trials. Information on drugs and new medical therapies are available to review. CenterWatch also provides patients with health and educational resources about clinical trials and other health information.”
National Center for Complementary and Alternative Medicine: The objectives of the NCCAM is to: “advance research on mind and body interventions, practices, and disciplines; advance research on CAM natural products; increase understanding of “real world” patterns and outcomes of CAM use and its integration into healthcare and health promotion; improve the capacity of the field to carry out rigorous research; and develop and disseminate objective, evidence-based information on CAM interventions.”

COURSE ACTIVITIES

Instructional Methods
This course consists of a series of online interactive and independent learning activities and discussion questions. The course is divided into eight weekly topic-related segments. Each week an overview of the topic-related content is presented with (a) topic learning objectives, (b) required and recommended readings, (c) areas for further study, (d) discussion questions, and (e) related course-assignment guidelines.

Weekly Assignments
Weekly course assignments are due at the end of each course week or as assigned. The time required to complete assignments will vary according to the nature of the assignment. For example, initial discussion question responses and the final course project will require differing amounts of student coursework time and effort to demonstrate competency. In this course students will participate in eight discussion assignments (one per week); complete four case studies in the form of papers; and complete four progress tests.

For information on the Weekly Assignments Late Policy, please see the Nursing Syllabus Standards & University Policy document provided in this course.

Your ePortfolio
The ePortfolio is an integral part of this class and, indeed, your entire degree program. Your ePortfolio will showcase the learning you have achieved through your time with American Sentinel University. The following artifact in this course must be uploaded to your ePortfolio:

Assignment 2-3 Case Studies

AMERICAN SENTINEL N521 ADVANCED PHARMACOLOGY ASSESSMENT METHODS & EVALUATION CRITERIA

Each course has individualized assessment methods and evaluation criteria. Specific course assessments and evaluation are described in this section of the syllabus. For the general Discussion Guidelines & Grading Rubric, please see the Nursing Syllabus Standards & University Policy document provided in this course.

Assignment Rubrics
Assignment rubrics are included with each assignment. Click on specific Assignments in the course to view each rubric.

Final Grade Calculation
Course grades are determined based on a percentage of the total possible points. Individual assignments will be allotted points based on specific criteria. The following grid illustrates how the points translate into a letter grade for the course.

Assessment	Weight Towards Final Grade
Weekly Discussions (8)	20%
Case Studies (3)	30%
Progress Tests (4)	50%