Cystic Fibrosis Discussion
Cystic Fibrosis Discussion
Cystic Fibrosis is an autosomal recessive disease that affects chromosome 7 on the DNA helix. The parents of the child with cystic fibrosis are both carriers of the disorder and likely have no symptoms and have no idea they are carriers. The disease is caused by a mutation in cystic fibrosis transmembrane regulator (CFTR). The CFTR regulates the flow of salt and fluids in and out of the cell. The CFTR protein provides instructions for the channel than transports negatively charged particles called chloride ions in and out of the cell and across the tissues. The lack of this channel causes the build-up of thick and sticky mucus because chloride helps with the movement of water across the tissues that assist with thinning the mucus. (CF Genetics: The Basics, 2020)
The organs that are affected most frequently are the lungs, digestive organs, pancreas, and reproductive organs. The thick mucus causes frequent lung infections and the cyst in the lungs. The thick mucus blocks the ducts of the pancreas and prevents the transport of digestive enzymes leading to malnutrition. The production of insulin is also affected by the thick mucus and cystic fibrosis patients can develop diabetes-related to this. Males with cystic fibrosis are infertile due to mucus plugging the vas deferens. Female with cystic fibrosis frequently have difficulty during pregnancy (Cystic Fibrosis, 2020).
Cystic fibrosis is a recessive disease and both parents must be carries to produce a child who has cystic fibrosis. The chances of two carriers having a child with cystic fibrosis are 25% and the chances that the child will have a 50% chance they are a carrier of the mutation and a 25% chance that the child will not be a carrier or have the disease. The person with cystic fibrosis has a child with a cystic fibrosis carrier then they have a 50% chance the child will have cystic fibrosis and a 50% chance they will be a carrier (Cystic Fibrosis, n.d.).
Cystic fibrosis is common in the Caucasian population with a frequency rate of 1 in 2500-3500 births. African American have a frequency rate of 1-17000 and Asian population have a frequency rate of 1-3100 births (CF Genetics: The Basics, 2020)
ORDER CUSTOM, PLAGIARISM-FREE PAPER
You must proofread your paper. But do not strictly rely on your computer’s spell-checker and grammar-checker; failure to do so indicates a lack of effort on your part and you can expect your grade to suffer accordingly. Papers with numerous misspelled words and grammatical mistakes will be penalized. Read over your paper – in silence and then aloud – before handing it in and make corrections as necessary. Often it is advantageous to have a friend proofread your paper for obvious errors. Handwritten corrections are preferable to uncorrected mistakes.
Use a standard 10 to 12 point (10 to 12 characters per inch) typeface. Smaller or compressed type and papers with small margins or single-spacing are hard to read. It is better to let your essay run over the recommended number of pages than to try to compress it into fewer pages.
Likewise, large type, large margins, large indentations, triple-spacing, increased leading (space between lines), increased kerning (space between letters), and any other such attempts at “padding” to increase the length of a paper are unacceptable, wasteful of trees, and will not fool your professor.
The paper must be neatly formatted, double-spaced with a one-inch margin on the top, bottom, and sides of each page. When submitting hard copy, be sure to use white paper and print out using dark ink. If it is hard to read your essay, it will also be hard to follow your argument.