MN553 Unit 9 Practice Quiz Latest 2019

A need to monitor drugs metabolized by 2D6 for toxicity

Increased dosages needed of drugs metabolized by 2D6, such as the selective serotonin reuptake inhibitors

Decreased conversion of codeine to morphine by CYP 2D6

The need for lowered dosages of drugs, such as beta blockers

Question 2 1 / 1 point

Rifampin is a nonspecific CYP450 inducer that may:

Question options:

Lead to toxic levels of rifampin and must be monitored closely

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Cause toxic levels of drugs, such as oral contraceptives, when coadministered

Induce the metabolism of drugs, such as oral contraceptives, leading to therapeutic failure

Cause nonspecific changes in drug metabolism

Question 3 1 / 1 point

Inhibition of P-glycoprotein by a drug such as quinidine may lead to:

Question options:

Decreased therapeutic levels of quinidine

Increased therapeutic levels of quinidine

Decreased levels of a coadministered drug, such as digoxin, that requires P-glycoprotein for absorption and elimination MN553 Unit 9 Practice Quiz Latest 2019

Increased levels of a coadministered drug, such as digoxin, that requires P-glycoprotein for absorption and elimination

Question 4 1 / 1 point

Warfarin resistance may be seen in patients with VCORC1 mutation, leading to:

Question options:

Toxic levels of warfarin building up

Decreased response to warfarin

Increased risk for significant drug interactions with warfarin

Less risk of drug interactions with warfarin

Question 5 1 / 1 point

Pharmacogenetic testing is required by the U.S. Food and Drug Administration prior to prescribing:

Question options:

Erythromycin

Digoxin

Cetuximab

Rifampin

Question 6 1 / 1 point

Carbamazepine has a Black Box Warning recommending testing for the HLA-B*1502 allele in patients with Asian ancestry prior to starting therapy due to:

Question options:

Decreased effectiveness of carbamazepine in treating seizures in Asian patients with the HLA-B*1502 allele

Increased risk for drug interactions in Asian patients with the HLA-B*1502 allele

Increased risk for Stevens-Johnson syndrome in Asian patients with HLA-B*1502 Allele

Patients who have the HLA-B*1502 allele being more likely to have a resistance to carbamazepine

Question 7 1 / 1 point

A genetic variation in how the metabolite of the cancer drug irinotecan SN-38 is inactivated by the body may lead to:

Question options:

Decreased effectiveness of irinotecan in the treatment of cancer

Increased adverse drug reactions, such as neutropenia

Delayed metabolism of the prodrug irinotecan into the active metabolite SN-38

Increased concerns for irinotecan being carcinogenic

Question 8 1 / 1 point

A good history of herb and supplement use is critical before prescribing because approximately ____ % of patients in the United States are using herbal products.

Question options:

Question 9 1 / 1 point

A potential harmful effect on patients who take some herbal medication is:

Question options:

Constipation

Lead poisoning

Diarrhea

Life-threatening rash

Question 10 1 / 1 point

A thorough understanding of herbs is critical to patient safety. An example is the use of cinnamon to treat type II diabetes. It is important the patient uses Ceylon cinnamon, as the commercially available cassia cinnamon contains:

Question options:

Coumadin, which may lead to bleeding problems MN553 Unit 9 Practice Quiz Latest 2019

Coumarin, which can cause liver and kidney damage

Cinnamic aldehyde, which is toxic to the kidney

Cinnamate eugenol, which is toxic to the liver

Question 11 1 / 1 point

Traditional Chinese medicine utilizes yin (cooling) versus yang (warming) in assessing and treating disease. Menopause is considered a time of imbalance, therefore the Chinese herbalist would prescribe:

Question options:

Herbs which are yang in nature

Herbs that are yin in nature

Ginger

Golden seal

Question 12 1 / 1 point

According to traditional Chinese medicine, if a person who has a fever is given a herb that is yang in nature, such as golden seal, the patient’s illness will:

Question options:

Get worse

Get better

Not be adequately treated

Need additional herbs to treat the yang

Question 13 1 / 1 point

In Ayurvedic medicine, treatment is based on the patient’s dominant dosha, which is referred to as the person’s:

Question options:

Vata

Pitta

Kapha

Prakriti

Question 14 1 / 1 point

When melatonin is used to induce sleep, the recommendation is that the patient:

Question options:

Take 10 mg 30 minutes before bed nightly

Take 1 to 5 mg 30 minutes before bed nightly

Not take melatonin more than three nights a week

Combine melatonin with zolpidem (Ambien) for the greatest impact on sleep

Question 15 1 / 1 point

In the United States, over-the-counter drugs are regulated by:

Question options:

No one. There is no oversight for over-the-counter medications.

The U.S. Food and Drug Administration Center for Drug Evaluation and Research

The U.S. Drug Enforcement Administration